Drug and Alcohol Findings

From Germany the first trial to rigorously test high doses of the muscle relaxant baclofen for the treatment of dependent drinking found post-detoxification drinking reductions of a magnitude rarely seen; safety issues remain, but it seems these can be managed with close monitoring and individualised dosing. Summary In the USA and Europe few medications haveRead More

The use of very high-doses of baclofen for the treatment of alcohol-dependence: a case series

Dr Renaud de Beaurepaire – Groupe Hospitalier Paul-Guiraud, Villejuif, France – Frontiers in Psychiatry – 10 ocotobre 2014 Baclofen, particularly high-dose baclofen, has recently emerged as a treatment of major interest for alcohol-dependence. However, baclofen has many potentially dangerous side effects, and the maximal dose of baclofen that may be used is a matter ofRead More

High-dose baclofen for treatment-resistant alcohol dependence

Pastor A, Jones DM, Currie J. – J Clin Psychopharmacol. J Clin Psychopharmacol. 2012 Feb 23. From the Department of Addiction Medicine, St Vincent’s Hospital, Melbourne, Australia. ABSTRACT: Alcohol dependence is associated with a wide array of physical and psychiatric complications and is a major cause of morbidity and mortality worldwide. Recent randomized trials ofRead More

Clinical Experience with Baclofen in the Management of Alcohol-Dependent Patients with Psychiatric Comorbidity: A Selected Case Series

Alcohol and Alcoholism – July 2011 – G.M. Dore, K. Lo, L. Juckes, S. Bezyan and N. Latt Le commentaire de G.M. Dore a propos de cet article « I became very interested in baclofen after this, and read your book from cover to cover, highlighting all the information I needed to study and use theRead More

déclaration publique du Pr. J. Borer, chef des services de médecine interne et de cardiologie à l’université de l’État de New York et de sommités médicales internationales au sujet de la découverte du Pr. O. Ameisen et de ses conséquences

le 23 janvier 2010 A qui de droit : C’est un honneur pour moi que de me joindre au Pr. Jean Dausset (Prix Nobel de Médecine), au Dr Jerome Posner (Professeur et titulaire de la chaire George Cotzias et directeur du laboratoire George Cotzias au Memorial Sloan-Kettering Cancer Center, Weill Medical College de l’Université Cornell)Read More